Liu Lab at Huazhong University of Science and Technology








RMalign: an RNA structural alignment tool based on a novel scoring function RMscore

RMalign is an RNA structural alignment program based on RMscore which describles the similarity of RNA structures. Two RNA structure coordinates in pdb format are input. RMalign will output the best alignment according to RMscore. A transformation matrix also is reported.

RMalign is available.

During developing RMalign, some datasets also are constructed. Result of benckmarking in balance-FSCOR. Rg vs RNA length RNA structure fragment to calulate the relationship between RNA length and aligned correlation coefficient PRMIE 2.0: SARA is replaced by RMalign. PRIME 2.0 significantly improved about 10% than previous PRIME. previous PRIME can be accessible at this site. The usage of PRIME 2.0 is similairty to previous PRIME. PRIME 2.0 can be accessible here.
INSTRUCTION for RMalign INSTALLATION:
download RMAlign package.
type "tar jxvf RMalign.tar.bz2" to uncompress and unpack the package.
type "./INSTALL.sh" to compile the programm.
type "source ~/.bashrc" to reload the ENV
CONTACT US:
Any questions about RMalign, please email to liushiyong@gmail.com.
Reference:
1. Jinfang Zheng, Juan Xie, Xu Hong & Shiyong Liu. RMalign: an RNA structural alignment tool based on a novel scoring function RMscore. BMC Genomics